CDMO Pharmaceutical Blog

Oral solid dosage (OSD) forms can exist in various types like tablets, capsules, gels, pills etc and vary according to the production techniques and facility designs involved. Oral solid dosage method is the most common dosage form as it is the most convenient method. They are administered orally which is later dissolved in the digestive system and absorbed into the bloodstream. They are easy to administer, can be self medicated and are easily distinguished from one another. The manufacturing methods for oral solid dosage forms are well developed and efficiently processed. Oral solid dosage forms consist of an active pharmaceutical ingredient (API) mixed with dry powder ingredients called excipients. They are of different forms such as tablets, capsules and pills. Tablets, which is the most commonly used oral solid dosage form, are made through compression technique. Capsules on the other hand are made through a coating process where active components and excipients form a coating arou...

Pre-formulation studies are crucial in the pharmaceutical industry, forming an integral part of drug formulation design. These studies involve investigating and analyzing the physicochemical properties of the drug molecule to enhance its specificity, activity, and efficacy. Additionally, they help in developing a robust dosage form that sustains the drug's shelf life. By studying the composition, structure, and biopharmaceutical properties of the drug, researchers can influence the drug's performance and dosage form, making pre-formulation studies a critical component of the formulation and drug development process. Importance and Objectives The primary aim of pre-formulation studies is to emphasize the safety and efficacy of the drug molecule by analyzing its physicochemical properties and nature. These studies ensure the development of a robust dosage form that is acceptable to patients. The evaluation of pre-formulation studies depends on the stability and oral bioavailabili...